DrugInvestigational line

Bortezomib

Proteasome inhibitor

Response rate
Single case report
Onset
Unknown
Route
SC or IV
Line
Investigational
IgM effect
Unknown
Evidence level
default

Evidence summary

Novel approach reported in 2024 in a patient without detectable serum IL-1β. Very preliminary.

Molecular targets

MoleculeRoleExpressionEvidence
NF-κBMaster transcription factorPersistently activestrong

Sources (1)

J6Kanabaj K et al. (2024) Modern look at Schnitzler syndromePubMed ↗