Bortezomib
Proteasome inhibitor
- Response rate
- Single case report
- Onset
- Unknown
- Route
- SC or IV
- Line
- Investigational
- IgM effect
- Unknown
Evidence summary
Novel approach reported in 2024 in a patient without detectable serum IL-1β. Very preliminary.
Molecular targets (1)
| Molecule | Role | Expression | Evidence |
|---|---|---|---|
| NF-κB | Master transcription factor | Persistently active | strong |