Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome

Key Findings

• ●Neutrophils identified as key cellular source of IL-1β in CAPS
• ●Neutrophil-specific knock-in mice develop CAPS

Referenced in (1 disease)

No validation events recorded yet. Source will be checked on the next kipine-source-validator run.