Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1β secretion

Tassi S, Carta S, Delfino L, et al.

Proc Natl Acad Sci USA · 2010

Grade Bbasic researchVerified
DOI ↗PubMed ↗

Key Findings

  • ●Altered redox state in CAPS monocytes
  • ●Spontaneous IL-1β secretion
  • ●Spontaneous ASC speck formation

Referenced in (1 disease)

Cryopyrin-Associated Periodic Syndromes

Validation history

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  1. passsource metadataJun 1, 2026, 01:59 PMby pubmed-api

    PMID/DOI resolved and recorded from PubMed E-utilities during SEO DOI backfill.

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ID: pmid-20445104DOI: 10.1073/pnas.1000779107PMID: 20445104