DrugAdjunctive line
Saline nasal irrigation
Mechanical clearance / mucosal hydration
- Response rate
- Symptom improvement
- Onset
- Days–weeks
- Route
- Nasal irrigation 1–2x daily
- Line
- Adjunctive
- IgM effect
- No direct effect
- Evidence level
- green
Evidence summary
High-volume saline irrigation improves mucociliary clearance and reduces symptom scores. Recommended as adjunctive therapy in all CRSwNP patients by EPOS 2020. Low cost, no side effects.
Sources (1)
D2Fokkens WJ et al. (2020) European Position Paper on Rhinosinusitis and Nasal Polyps 2020 (EPOS 2020)DOI ↗