Saline nasal irrigation

Mechanical clearance / mucosal hydration

Response rate
Symptom improvement
Onset
Days–weeks
Route
Nasal irrigation 1–2x daily
Line
Adjunctive
IgM effect
No direct effect

Evidence summary

High-volume saline irrigation improves mucociliary clearance and reduces symptom scores. Recommended as adjunctive therapy in all CRSwNP patients by EPOS 2020. Low cost, no side effects.

Sources (1)

D2Fokkens WJ et al. (2020) European Position Paper on Rhinosinusitis and Nasal Polyps 2020 (EPOS 2020) · RhinologyDOI