Neutrophilic Urticarial Dermatosis: A Window into Systemic Inflammation and Autoimmune Disorders.

Key Findings

• ●Comprehensive review of neutrophilic urticarial dermatosis (NUD) across five major conditions: Schnitzler syndrome, Still's disease, CAPS, SLE, and VEXAS syndrome
• ●Proposes a diagnostic framework for NUD with skin biopsy as the central tool
• ●Discusses neutrophilic epitheliotropism as a histological hallmark in Schnitzler syndrome
• ●NUD may serve as an early cutaneous indicator of occult systemic autoinflammatory disease
• ●Multidisciplinary assessment recommended for definitive diagnosis of underlying etiology

Referenced in (1 disease)