Systemic Mastocytosis: Molecular Landscape and Implications for Treatment.

Key Findings

• ●Comprehensive review of KIT D816V downstream signaling: STAT5-PI3K-AKT-mTOR axis
• ●PI3K, STAT5, NF-kB, mTORC2, PKCdelta as key mediators of oncogenic KIT signaling

Referenced in (1 disease)

1. passsource metadataJun 1, 2026, 04:57 PMby pubmed-api

   Identifier re-resolved by title (deeper second pass): prior entry (doi-10-3390-cancers13133100) had a fabricated/wrong identifier; repointed to this record via PubMed/Crossref.

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