INSAID variant classification and Eurofever criteria guide optimal treatment strategy in patients with TRAPS: data from the Eurofever Registry
Papa R, Lane T, Minden K, Touitou I, Cantarini L, Cattalini M, Obici L, et al.
J Allergy Clin Immunol Pract · 2021
Grade Bcohortn=226
Key Findings
- ●226 patients classified by INSAID: Group A (pathogenic) 56%, Group B (uncertain) 35%, Group C (benign) 9%
- ●Anti-IL-1 drugs achieved >85% complete response in patients meeting Eurofever criteria
- ●No patients on anti-IL-1 treatment developed AA amyloidosis
- ●16% of Group A patients developed AA amyloidosis
Referenced in (1 disease)
ID: pmid-33181346DOI: 10.1016/j.jaip.2020.09.060PMID: 33181346