Canakinumab for treatment of adult-onset Still's disease to achieve reduction of arthritic manifestation (CONSIDER): phase II, randomised, double-blind, placebo-controlled trial

Kedor C, Listing J, Zernicke J, et al.

Ann Rheum Dis · 2020

Grade BRCTn=35

Key Findings

  • 67% canakinumab vs 41% placebo achieved primary endpoint (p=0.18, underpowered)
  • Trial terminated prematurely due to disease rarity and EMA conditional approval

Referenced in (1 disease)

ID: pmid-32404342PMID: 32404342