Revisiting TNF Receptor-Associated Periodic Syndrome (TRAPS): Current Perspectives

Cudrici C, Bhattacharya S, Bhattacharya M

Int J Mol Sci · 2020

Grade Bnarrative reviewUnverified

Key Findings

  • Comprehensive review of TRAPS pathogenesis, genetics, and treatment
  • Multiple non-exclusive pathogenic mechanisms: shedding defect, ER stress, ROS, autophagy
  • IL-1 inhibitors established as first-line treatment

Referenced in (1 disease)

Validation history

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ID: pmid-32380704DOI: 10.3390/ijms21093263PMID: 32380704