CXCR4 mutations affect presentation and outcomes in patients with WM: a systematic review

Key Findings

• ●Pooled CXCR4 mutation prevalence 31%; 34% in MYD88-mutated, 5% in MYD88-WT
• ●Associated with higher IgM levels and hyperviscosity risk
• ●Did not impact overall survival despite worse treatment response

Referenced in (1 disease)

1. passsource metadataJun 1, 2026, 04:40 PMby pubmed-api

   Stored DOI was incorrect; corrected to the PubMed-registered DOI (verified to resolve to this article).

   tools: pubmed.esummary, crossref.works