Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis.

Hoermann G, Gleixner KV, Dinu GE, et al.

eBioMedicine · 2019

Grade Bbasic researchVerified
DOI ↗PubMed ↗

Key Findings

  • ●D816V mutation arises in early hematopoietic stem/progenitor cells
  • ●Mutation burden is low in progenitors but increases in mature mast cells

Referenced in (1 disease)

Systemic Mastocytosis

Validation history

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  1. passsource metadataJun 1, 2026, 04:40 PMby pubmed-api

    Identifier corrected: prior entry (doi-10-1016-j-ebiom-2019-04-007) had a wrong PMID/DOI pointing to an unrelated paper; re-resolved by title to this record via PubMed/Crossref.

    tools: pubmed.esummary, crossref.works

ID: pmid-30975542DOI: 10.1016/j.ebiom.2019.03.089PMID: 30975542