What is the best first-line treatment for POEMS syndrome: autologous transplantation, melphalan and dexamethasone, or lenalidomide and dexamethasone?

Key Findings

• ●Compared ASCT (n=165), MDex (n=79), LDex (n=103) as first-line therapy
• ●ASCT achieved highest hematologic CR (49.7%)
• ●Neurological remission similar across groups (~93%)
• ●3-year PFS 80.5%, 3-year OS 90.8% overall

Referenced in (1 disease)

1. passsource metadataJun 1, 2026, 04:40 PMby pubmed-api

   Stored DOI was incorrect; corrected to the PubMed-registered DOI (verified to resolve to this article).

   tools: pubmed.esummary, crossref.works