Adult-Onset Still's Disease: Molecular Pathophysiology and Therapeutic Advances.

Sfriso P, Bindoli S, Galozzi P, et al.

Int J Mol Sci · 2022

Key Findings

  • NLRP3 inflammasome dysregulation central to pathogenesis
  • NETs activate NLRP3 and inflammatory macrophages creating self-amplifying loop
  • Comprehensive review of emerging therapies including JAK inhibitors

Referenced in (1 disease)

Validation history

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  1. passsource metadataJun 1, 2026, 04:40 PMby pubmed-api

    Identifier corrected: prior entry (pmid-36430339) had a wrong PMID/DOI pointing to an unrelated paper; re-resolved by title to this record via PubMed/Crossref.

    tools: pubmed.esummary, crossref.works

ID: pmid-30069732DOI: 10.1007/s40265-018-0956-9PMID: 30069732