Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still's disease

Gabay C, Fautrel B, Rech J, et al.

Ann Rheum Dis · 2018

Grade Ccohortn=23

Key Findings

  • First clinical trial of IL-18 inhibition in AOSD
  • Favorable safety profile with early signs of efficacy at both 80mg and 160mg doses

Referenced in (1 disease)

ID: pmid-29472362PMID: 29472362