Elevated expression of the NLRP3 inflammasome and its correlation with disease activity in adult-onset Still disease

Chen DY, Lan JL, Lin FJ, Hsieh TY

J Rheumatol · 2017

Key Findings

  • NLRP3, caspase-1, and IL-1β significantly elevated in AOSD PBMCs
  • NLRP3 expression correlated with disease activity

Referenced in (1 disease)

Validation history

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  1. passsource metadataJun 1, 2026, 08:55 PMby pubmed-api

    Confirmed as the real support for the NLRP3-inflammasome-in-AOSD claim (Hsieh 2017, already cited as B4); removed a redundant fabricated duplicate citation (former B5).

    tools: pubmed.esummary, crossref.works

ID: pmid-28507179DOI: 10.3899/jrheum.161354PMID: 28507179