Aspirin-exacerbated respiratory disease — genetic and molecular mechanisms

Laidlaw TM, Boyce JA

N Engl J Med · 2016

Grade Bnarrative review

Key Findings

  • ALOX5, LTC4S, CYSLTR variants in AERD
  • Cysteinyl leukotriene overproduction defines AERD
  • Pharmacogenomic implications for LTRA therapy

Referenced in (1 disease)

ID: pmid-26840139DOI: 10.1056/NEJMra1500579PMID: 26840139