Aspirin-exacerbated respiratory disease — genetic and molecular mechanisms

Laidlaw TM, Boyce JA

N Engl J Med · 2016

Key Findings

  • ALOX5, LTC4S, CYSLTR variants in AERD
  • Cysteinyl leukotriene overproduction defines AERD
  • Pharmacogenomic implications for LTRA therapy

Referenced in (1 disease)

Validation history

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  1. passsource metadataJun 1, 2026, 04:40 PMby pubmed-api

    Stored DOI was incorrect; corrected to the PubMed-registered DOI (verified to resolve to this article).

    tools: pubmed.esummary, crossref.works

ID: pmid-26840139DOI: 10.1056/NEJMcibr1514013PMID: 26840139