The genomic landscape of Waldenstrom macroglobulinemia is characterized by highly recurring MYD88 and WHIM-like CXCR4 mutations, and small somatic deletions associated with B-cell lymphomagenesis.

Key Findings

• ●Comprehensive genomic characterisation of WM
• ●Identified CXCR4 WHIM-like mutations in ~30% of patients
• ●Mapped additional recurrent somatic mutations in ARID1A, TP53, CD79B

Referenced in (1 disease)

1. passsource metadataJun 1, 2026, 04:40 PMby pubmed-api

   Identifier corrected: prior entry (pmid-25320245) had a wrong PMID/DOI pointing to an unrelated paper; re-resolved by title to this record via PubMed/Crossref.

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