DNASE1L3 mutations in hypocomplementemic urticarial vasculitis syndrome

Özçakar ZB, Foster J 2nd, Diaz-Horta O, Kasapcopur O, Fan YS, Yalçınkaya F, Tekin M

Arthritis Rheum · 2013

Grade Acohort

Key Findings

  • Identified DNASE1L3 loss-of-function mutations as the genetic cause of familial HUVS
  • Homozygous frameshift mutation c.289_290delAC in one family
  • Autosomal recessive inheritance pattern established

Referenced in (1 disease)

ID: pmid-23666765DOI: 10.1002/art.38010PMID: 23666765