MYD88 L265P mutation in Waldenstrom macroglobulinemia

Key Findings

• ●MYD88 L265P acquired in 79% of WM patients by Sanger sequencing
• ●MYD88 locus altered in 91% including copy number gains at 3p22
• ●MYD88 mutations activate NF-kB signaling

Referenced in (1 disease)