MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

Key Findings

• ●Identified MYD88 L265P in 91% of WM patients by whole-genome sequencing
• ●Mutation absent in paired normal tissue and healthy donor B cells
• ●Absent or rarely expressed in myeloma, marginal-zone lymphoma, and IgM-MGUS

Referenced in (1 disease)