Long-term clinical profile of children with the low-penetrance R92Q mutation of the TNFRSF1A gene
Pelagatti MA, Meini A, Caorsi R, Cattalini M, Federici S, Zulian F, Calcagno G, Tommasini A, Bossi G, Gattorno M
Arthritis Rheum · 2011
Grade Bcohort
Key Findings
- ●R92Q associated with milder disease in children vs structural mutations
- ●Higher rate of spontaneous resolution with R92Q
- ●Lower amyloidosis risk compared to structural mutations
Referenced in (1 disease)
ID: pmid-21225694DOI: 10.1002/art.30164PMID: 21225694