Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade.

Growney JD, Clark JJ, Adelsperger J, et al.

Blood · 2005

Key Findings

  • STAT5-PI3K cascade essential for KIT D816V-mediated MC growth and survival
  • Knockdown of Stat5 or Akt inhibits neoplastic KIT D816V+ MC growth

Referenced in (1 disease)

Validation history

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  1. passsource metadataJun 1, 2026, 04:57 PMby pubmed-api

    Identifier re-resolved by title (deeper second pass): prior entry (doi-10-1182-blood-2004-12-4767) had a fabricated/wrong identifier; repointed to this record via PubMed/Crossref.

    tools: pubmed.esummary, crossref.works

ID: pmid-18579792DOI: 10.1182/blood-2007-09-115477PMID: 18579792