Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade.
Growney JD, Clark JJ, Adelsperger J, et al.
Blood · 2005
Key Findings
- ●STAT5-PI3K cascade essential for KIT D816V-mediated MC growth and survival
- ●Knockdown of Stat5 or Akt inhibits neoplastic KIT D816V+ MC growth
Referenced in (1 disease)
Validation history
Full log →- passsource metadataJun 1, 2026, 04:57 PMby pubmed-api
Identifier re-resolved by title (deeper second pass): prior entry (doi-10-1182-blood-2004-12-4767) had a fabricated/wrong identifier; repointed to this record via PubMed/Crossref.
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ID: pmid-18579792DOI: 10.1182/blood-2007-09-115477PMID: 18579792