Genetic risk factors for CRSwNP: IL-33/ST2 and TSLP pathway variants

Portelli MA, et al.

J Allergy Clin Immunol · 2020

Grade BGWAS

Key Findings

  • IL33, IL1RL1 (ST2), TSLP variants associated with CRSwNP risk
  • Shared genetic architecture with asthma
  • Alarmin pathway genetically implicated

Referenced in (1 disease)

ID: doi-10-1016-j-jaci-2020-01-023DOI: 10.1016/j.jaci.2020.01.023