Molecule
S. aureus enterotoxins
Superantigen / disease perpetuator
- Expression change
- Present in polyp tissue
- Evidence level
- strong
Role in pathogenesis
Staphylococcus aureus enterotoxins act as superantigens, driving polyclonal T-cell activation and local IgE production within polyps. Create a self-sustaining inflammatory niche independent of systemic allergy.