DrugAlternative line

Epinephrine autoinjector

Adrenergic agonist — emergency anaphylaxis treatment

Response rate
Life-saving in anaphylaxis
Onset
Minutes
Route
IM autoinjector (0.3mg)
Line
Alternative
IgM effect
N/A
Evidence level
green

Evidence summary

All SM patients should carry at least one epinephrine autoinjector. Essential for emergency treatment of anaphylaxis, which occurs at 7.2x the rate of the general population. Reverses vasodilation, bronchospasm, and airway edema.

Sources (2)

DetailsLim KH et al. (2016) Risk of solid cancer, cardiovascular disease, anaphylaxis, osteoporosis and fractures in patients with systemic mastocytosis: a nationwide population-based studyDOI ↗
DetailsCastells M et al. (2022) Treatment of Indolent and Advanced Systemic MastocytosisDOI ↗