Eotaxin-3 (CCL26)
Eosinophil chemoattractant
- Expression
- Elevated
- Evidence level
- strong
Role in pathogenesis
IL-4/IL-13 induce eotaxin-3 production by epithelial cells. Eotaxin-3 is the most potent eosinophil chemoattractant and correlates with tissue eosinophilia in polyps.
Sources (1)
P2Bachert C et al. (2015) Endotype-driven care pathways in patients with chronic rhinosinusitis · J Allergy Clin ImmunolDOI ↗