Systemic Mastocytosis: Molecular Landscape and Implications for Treatment

Chatterjee A, Ghosh J, Bhatt N

Cancers · 2021

Grade Bnarrative review
DOI ↗

Key Findings

  • ●Comprehensive review of KIT D816V downstream signaling: STAT5-PI3K-AKT-mTOR axis
  • ●PI3K, STAT5, NF-kB, mTORC2, PKCdelta as key mediators of oncogenic KIT signaling

Referenced in (1 disease)

Systemic Mastocytosis
ID: doi-10-3390-cancers13133100DOI: 10.3390/cancers13133100