Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis

Hoermann G, Gleixner KV, Dinu GE, et al.

eBioMedicine · 2019

Grade Bbasic research
DOI ↗

Key Findings

  • ●D816V mutation arises in early hematopoietic stem/progenitor cells
  • ●Mutation burden is low in progenitors but increases in mature mast cells

Referenced in (1 disease)

Systemic Mastocytosis
ID: doi-10-1016-j-ebiom-2019-04-007DOI: 10.1016/j.ebiom.2019.04.007