Rituximab
Anti-CD20 (B-cell depletion)
- Response rate
- Ineffective on inflammation
- Onset
- —
- Route
- IV infusion
- Line
- Not recommended
- IgM effect
- Reduces IgM
Evidence summary
Depletes B cells and can reduce IgM, but doesn't control inflammatory symptoms.
Molecular targets (1)
| Molecule | Role | Expression | Evidence |
|---|---|---|---|
| IgM (monoclonal) | Diagnostic paraprotein | Present (obligate) | established |