IL-18
NK cell activator
- Expression
- Elevated
- Evidence level
- moderate
Role in pathogenesis
Another inflammasome product (cleaved by caspase-1 alongside IL-1β). Elevated levels may drive IgM-producing B-cell expansion.
Sources (1)
B3Regnault V et al. (2019) PBMC studies: spontaneous IL-1β release · Scand J Rheumatol